ANALYSIS OF POLYMORPHISMS, PROMOTER METHYLATION, AND MRNA EXPRESSION PROFILE OF MATERNAL AND PLACENTAL P53 AND P21 GENES IN PREECLAMPTIC AND NORMOTENSIVE PREGNANT WOMEN

Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women

Abstract Background Preeclampsia (PE), as a multisystem disorder, is associated with maternal hypertension and proteinuria.Apoptosis seems to be involved in the pathophysiology of PE, although its precise pathogenic mechanisms are not well established.In this study, we aimed to identify the association between maternal TP53-rs1042522, P21-rs1801270

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Honour Killing in Historical Context and Islamic Law

The practice of honour killing is a multilayered phenomenon with regard to causes emanating through macro as well as micro level parameters; making it a complex form of disorder in a society, L-Glutamine and hence considered one of major social and cultural crimes which human societies fall victim to.It cuts through far past and influences various

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Therapeutic Effects of Canagliflozin and Zinc Sulphate Alone and in Combination on Pancreatic Histology in Type-2 Diabetic Rat Model

Introduction: Diabetes Mellitus is a common metabolic syndrome characterized by persistently elevated blood glucose levels.Canagliflozin Cooktop Knob Seal is an SGLT-2 inhibitor that controls hyperglycemia by reducing the reabsorption of filtered glucose and excreting it in the urine.Zinc sulphate exhibits some beneficial role in diabetes mellitus

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